Which neurotransmitter is primarily associated with inhibitory neurotransmission in the brain?

Study for the Nightingale Psychology Exam with our quiz. Get ready with flashcards and multiple choice questions, each with hints and explanations. Boost your psychology knowledge!

Multiple Choice

Which neurotransmitter is primarily associated with inhibitory neurotransmission in the brain?

Inhibitory signaling in the brain is mainly mediated by GABA, the gamma-aminobutyric acid neurotransmitter. When GABA binds to its receptors, it makes neurons less likely to fire. The fast, primary action is through GABA-A receptors, which open chloride channels and cause hyperpolarization. A slower, longer-lasting effect comes from GABA-B receptors, which open potassium channels and also reduce excitability. This inhibition helps balance neural activity and prevents overexcitation. Dopamine modulates reward, motivation, and movement and can have varying effects depending on receptor and region, but it is not primarily inhibitory. Serotonin also modulates mood and other functions with diverse receptor actions, not solely inhibitory. Glutamate is the main excitatory neurotransmitter, driving increased neuronal firing. Therefore, the neurotransmitter most associated with inhibitory signaling is GABA.

Inhibitory signaling in the brain is mainly mediated by GABA, the gamma-aminobutyric acid neurotransmitter. When GABA binds to its receptors, it makes neurons less likely to fire. The fast, primary action is through GABA-A receptors, which open chloride channels and cause hyperpolarization. A slower, longer-lasting effect comes from GABA-B receptors, which open potassium channels and also reduce excitability. This inhibition helps balance neural activity and prevents overexcitation.

Dopamine modulates reward, motivation, and movement and can have varying effects depending on receptor and region, but it is not primarily inhibitory. Serotonin also modulates mood and other functions with diverse receptor actions, not solely inhibitory. Glutamate is the main excitatory neurotransmitter, driving increased neuronal firing. Therefore, the neurotransmitter most associated with inhibitory signaling is GABA.

More practice questions